Sleep Wake Flip-Flop 

Overview

This app visualizes the neurological "flip-flop" switch model of sleep and wakefulness. It demonstrates how the brain transitions between sleeping and waking states via mutual inhibition, preventing the body from existing in a half-awake/half-asleep state.

How to Use

The application presents two main systems: the Sleep System (vlPOA) and the Arousal System (Acetylcholine, Noradrenalin, Serotonin, Histamine).

• Click "Adenosine": Simulates the build-up of sleep pressure. The Sleep System glows green (stimulated), the Arousal System glows red (inhibited), and the right-pointing arrow glows red, demonstrating the Sleep System actively turning off the Arousal System.
• Click "Orexin": Simulates the release of wake-promoting neurotransmitters. The Arousal System glows green (stimulated), the Sleep System glows red (inhibited), and the left-pointing arrow glows red, demonstrating the Arousal System actively turning off the Sleep System.
• Click "Reset to Neutral": Clears all simulated interactions and returns the diagram to its baseline, inactive state.

Visual Key

• Green Glow: Indicates neurological stimulation / activation.
• Red Glow (Boxes): Indicates neurological inhibition / suppression.
• Red Glow (Arrows): Indicates the active pathway of mutual inhibition.